Detalhe da pesquisa
1.
Illuminating G-Protein-Coupling Selectivity of GPCRs.
Cell
; 177(7): 1933-1947.e25, 2019 06 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31160049
2.
Whole-genome CRISPR screening identifies PI3K/AKT as a downstream component of the oncogenic GNAQ-focal adhesion kinase signaling circuitry.
J Biol Chem
; 299(2): 102866, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36596361
3.
Gαs-Protein Kinase A (PKA) Pathway Signalopathies: The Emerging Genetic Landscape and Therapeutic Potential of Human Diseases Driven by Aberrant Gαs-PKA Signaling.
Pharmacol Rev
; 73(4): 155-197, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34663687
4.
Host-based Prophylaxis Successfully Targets Liver Stage Malaria Parasites.
Mol Ther
; 23(5): 857-865, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25648263
5.
Susceptibility to Plasmodium yoelii preerythrocytic infection in BALB/c substrains is determined at the point of hepatocyte invasion.
Infect Immun
; 83(1): 39-47, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25312960
6.
SSP3 is a novel Plasmodium yoelii sporozoite surface protein with a role in gliding motility.
Infect Immun
; 82(11): 4643-53, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25156733
7.
Catalytic site mutations confer multiple states of G protein activation.
Sci Signal
; 16(772): eabq7842, 2023 02 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36787384
8.
High-throughput chemogenetic drug screening reveals PKC-RhoA/PKN as a targetable signaling vulnerability in GNAQ-driven uveal melanoma.
Cell Rep Med
; 4(11): 101244, 2023 11 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37858338
9.
Cyclosporine Induces Fenestra-Associated Injury in Human Renal Microvessels In Vitro.
ACS Biomater Sci Eng
; 8(1): 196-207, 2022 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34927415
10.
Focal Adhesion Kinase (FAK)-Hippo/YAP transduction signaling mediates the stimulatory effects exerted by S100A8/A9-RAGE system in triple-negative breast cancer (TNBC).
J Exp Clin Cancer Res
; 41(1): 193, 2022 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35655319
11.
A genome-wide CRISPR-Cas9 screen identifies CENPJ as a host regulator of altered microtubule organization during Plasmodium liver infection.
Cell Chem Biol
; 29(9): 1419-1433.e5, 2022 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35738280
12.
EGFR Regulates the Hippo pathway by promoting the tyrosine phosphorylation of MOB1.
Commun Biol
; 4(1): 1237, 2021 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34725466
13.
Synthetic Lethal Screens Reveal Cotargeting FAK and MEK as a Multimodal Precision Therapy for GNAQ-Driven Uveal Melanoma.
Clin Cancer Res
; 27(11): 3190-3200, 2021 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33568347
14.
G Protein-Coupled receptors and heterotrimeric G proteins as cancer drivers.
FEBS Lett
; 594(24): 4201-4232, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33270228
15.
Muscarinic receptors promote castration-resistant growth of prostate cancer through a FAK-YAP signaling axis.
Oncogene
; 39(20): 4014-4027, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32205868
16.
Liver stage malaria infection is controlled by host regulators of lipid peroxidation.
Cell Death Differ
; 27(1): 44-54, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31065106
17.
Alterations in Phosphorylation of Hepatocyte Ribosomal Protein S6 Control Plasmodium Liver Stage Infection.
Cell Rep
; 26(12): 3391-3399.e4, 2019 03 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30893610
18.
Structure of the C-terminal guanine nucleotide exchange factor module of Trio in an autoinhibited conformation reveals its oncogenic potential.
Sci Signal
; 12(569)2019 02 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30783010
19.
A Platform of Synthetic Lethal Gene Interaction Networks Reveals that the GNAQ Uveal Melanoma Oncogene Controls the Hippo Pathway through FAK.
Cancer Cell
; 35(3): 457-472.e5, 2019 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30773340
20.
Identifying host regulators and inhibitors of liver stage malaria infection using kinase activity profiles.
Nat Commun
; 8(1): 1232, 2017 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29089541